Activity-based CDK16/cyclin Y kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
CDK16/Cyclin Y
Enzyme
Human CDK16/Cyclin Y
HGNC
CDK16/CCNY
Synonym
PCTAIRE1, PCTAIRE, PCTGAIRE, PCTK1
Substrates
RB protein, 3 µM
ATP 10 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
Scientific Information
Screening Location
Malvern, USA
Reference compound IC50 for CDK16/Cyclin Y
![](https://www.reactionbiology.com/wp-content/uploads/2023/07/CDK16_cyclin_Y_Kin_Malvern.png)