Caspase 2 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Caspase 2
Enzyme
Human Caspase 2
Synonym
Neural precursor cell expressed developmentally down-regulated protein 2, Protease ICH-1, CASP2, ICH1, NEDD2
Substrates
Fluorogenic peptide Ac-LEHD-AMC, 5 µM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| IETD-CHO | 246 |
Scientific Information
P42575 (https://www.uniprot.org/uniprotkb/P42575/entry)
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assay Services.
Reference compound IC50 for Caspase 2
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