Caspase 4 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Caspase 4
Enzyme
Human Caspase 4
Synonym
ICE(rel)-II, Protease ICH-2, Protease TX, CASP4, ICH2
Substrates
Fluorogenic peptide [Ac-LEHD-AMC], 5 µM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (µM) |
|---|---|
| IETD-CHO | 1.9 |
Scientific Information
P49662 (http://www.uniprot.org/uniprot/P49662)
Screening Location
Malvern, USA
Reference compound IC50 for Caspase 4
PDF