Cathepsin D Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Cathepsin D
Enzyme
Human Cathepsin D
Synonym
CTSD, CPSD, CATD
Substrates
Fluorogenic peptide [MCA- PLGL-Dap (Dnp)-AR-NH2], 2 µM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (pM) |
|---|---|
| Pepstatin A | 68 |
Scientific Information
P07339 (http://www.uniprot.org/uniprot/P07339)
Screening Location
Malvern, USA
Reference compound IC50 for Cathepsin D
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