Cathepsin K Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Cathepsin K
Enzyme
Human Cathepsin K
Synonym
CTSK, Cathepsin O/O2/X
Substrates
Fluorogenic peptide [Z-FR-AMC], 5 μM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| E-64 | 0.37 |
Scientific Information
P43235 (http://www.uniprot.org/uniprot/P43235)
Screening Location
Malvern, USA
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