Factor XIa Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Factor XIa
Enzyme
Human Factor XIa
Synonym
Coagulation factor XIa, Plasma thromboplastin antecedent, PTA, F11
Substrates
Fluorogenic peptide (Boc-Glu(OBzl)-Ala-Arg)-MCA, 10 µM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Gabexate mesylate | 231 |
Scientific Information
P03951 (https://www.uniprot.org/uniprotkb/P03951/entry)
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assay Services
Reference compound IC50 for Factor XIa
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