Kallikrein 2 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Kallikrein 2
Enzyme
Kallikrein 2
Synonym
KLK2, Glandular kallikrein-1, hGK-1, Tissue kallikrein-2
Substrates
Fluorogenic substrate PFR-AMC, 10 µM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (µM) |
|---|---|
| Gabexate Mesylate | 0.38 |
| Leupeptin | 11.8 |
Scientific Information
P20151 (http://www.uniprot.org/uniprot/P20151)
Screening Location
Malvern, USA
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