HSP90b Heat Shock Protein Assay for compound screening and profiling via fluorescence polarization-based quantification of enzyme activity.
Target Overview
CAT#
HSP90b
Enzyme
Human HSP90b
Synonym
Heat shock protein HSP 90-beta, Heat shock 84 kDa, HSP90AB1, HSP90B, HSPC2, HSPCB, HS90B
Substrate
Geldanamycin, 5 nM
Assay Properties
Readout
Binding competition with fluorescent geldanamycin
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Geldanamycin | 50.3 |
| Radicicol | 89.0 |
Scientific Information
P08238 (http://www.uniprot.org/uniprot/P08238)
Screening Location
Malvern, USA
Further information
More information can be found on our website Heat Shock Protein Assays.
Control Compound IC50 for HSP90b
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