Nucleotidyltransferase cGAS (AA 157-522) assay with surface plasmon resonance (SPR) technique
Target Overview
Target
Human cGAS fragment (AA 157-522)
HGNC symbol
CGAS (AA 157-522)
Synonyms
Cyclic GMP-AMP synthase, cGAMP synthase
Scientific information
Screening location
Malvern, PA, USA
Further information
More information can be found on our website SPR Assay Services for Drug Discovery
Binding kinetics and steady state affinity of PF-06928215 to cGAS (aa157-522)
The data was collected on a Biacore 8K using multi-cycle kinetics. cGAS (AA 157-522) was immobilized to the sensor chip and the binding of PF-06928215 was measured. The binding data was analyzed using both a 1:1 kinetic binding model and a steady state affinity model.
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