ATAD2-His Reader Domain Assay for compound screening and profiling using the AlphaScreen assay format to measure compound binding to the target.
Target Overview
CAT#
ATAD2-His
Enzyme
Human ATAD2-His
Synonyms
ATPase family AAA domain-containing protein 2, AAA nuclear coregulator cancer-associated protein, ANCCA, L16, PRO2000
Substrates
Histone H4 peptide (1-21) K5/8/12/16Ac
Assay Properties
Reaction
AlphaScreen Binding assay
Readout
Fluorescence
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| JQ-1 | 35,000 |
| Bromosporine | 89,000 |
| SGC-CBP30 | 70,000 |
| GSK2801 | 113,000 |
Scientific Information
Q6PL18 (http://www.uniprot.org/uniprot/Q6PL18)
Screening Location
Malvern, USA
Further information
More information can be found on our website Reader Domain Assay Services.
Reference Compound IC50 for ATAD2
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