BRD2-Tndm-His Reader Domain Assay for compound screening and profiling using the AlphaScreen assay format to measure compound binding to the target.
Target Overview
CAT#
BRD2-Tandem
Enzyme
Human BRD2-Tandem
Synonyms
Bromodomain-containing protein 2 domain 1 and domain 2, O27.1.1, Really interesting new gene 3 protein, KIAA9001, RING3
Substrates
Histone H4 peptide (1-21) K5/8/12/16Ac
Assay Properties
Reaction
AlphaScreen Binding assay
Readout
Fluorescence
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| JQ-1 | 75 |
| PFI-1 | 1,200 |
Scientific Information
P25440 (http://www.uniprot.org/uniprot/P25440)
Screening Location
Malvern, USA
Further information
More information can be found on our website Reader Domain Assay Services.
Reference Compound IC50 for BRD2-T
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