SMARCA4-His Reader Domain Assay for compound screening and profiling using the AlphaScreen assay format to measure compound binding to the target.
Target Overview
CAT#
SMARCA4-His
Enzyme
Human SMARCA4-His
Synonyms
Transcription activator BRG1, ATP-dependent helicase SMARCA4, BAF190A, BRG1, SNF2B, SNF2L4
Substrates
Histone H3 peptide (1-30) K4/18/23/27Ac
Assay Properties
Reaction
AlphaScreen Binding assay
Readout
Fluorescence
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| PFI-3 | 420 |
| Bromosporine | 45,000 |
Scientific Information
P51532 (http://www.uniprot.org/uniprot/P51532)
Screening Location
Malvern, USA
Further information
More information can be found on our website Reader Domain Assay Services.
Reference Compound IC50 for SMARCA4
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