HDAC1 Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
HDAC1
Enzyme
Human HDAC1
Synonyms
Histone deacetylase 1, Class I
Substrates
Fluorogenic peptide from p53 residues 379-382 (RHKKAc), 10 μM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Trichostatin A | 3.31 |
| SAHA | 77.0 |
| Panobinostat | 1.44 |
Scientific Information
Q13547 (http://www.uniprot.org/uniprot/Q13547)
Screening Location
Malvern, USA
Further information
More information can be found on our website HDAC Assay (Histone Deacetylase Assay) and Sirtuin Assay Services.
Reference Compound IC50 for HDAC1
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