HDAC3/NCOR2 Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
HDAC3/NCOR2
Enzyme
Human HDAC3/NCOR2
Synonyms
Histone Deacetylase 3, Class I NCOR2: Nuclear receptor corepressor 2, CTG repeat protein 26, SMAP270
Substrates
Fluorogenic peptide from p53 residues 379-382 (RHKKAc), 10 μM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Trichostatin A | 5.16 |
| SAHA | 64.3 |
| Panobinostat | 1.12 |
Scientific Information
Screening Location
Malvern, USA
Further information
More information can be found on our website HDAC Assay (Histone Deacetylase Assay) and Sirtuin Assay Services.
Reference Compound IC50 for HDAC3
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