HDAC6 Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
HDAC6
Enzyme
Human HDAC6
Synonyms
Histone Deacetylase 6, Class IIb
Substrates
Fluorogenic peptide from p53 residues 379-382 (RHKKAc), 10 μM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Trichostatin A | 1.18 |
| SAHA | 10.5 |
| Panobinostat | 2.51 |
Scientific Information
Q9UBN7 (http://www.uniprot.org/uniprot/Q9UBN7)
Screening Location
Malvern, USA
Further information
More information can be found on our website HDAC Assay (Histone Deacetylase Assay) and Sirtuin Assay Services.
Reference Compound IC50 for HDAC6
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