Tryptase b2 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Tryptase b2
Enzyme
Tryptase beta 2
Species
Human recombinant
Synonyms
TPSB2, TPS2, TryptaseB, TryptaseC
Scientific Information
P20231 (https://www.uniprot.org/uniprotkb/A0A087WUI4)
Assay Properties
Substrates
Fluorogenic peptide Z-GPR-AMC, 10 µM
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Gabexate Mesylate | 11.4 |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assays
Reference compound inhibition of Tryptase b2
PDF