TRPM7/CHAK1 Kinase Assay Service

Activity-based TRPM7/CHAK1 kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

TRPM7/CHAK1

Enzyme

Human TRPM7/CHAK1

HGNC

TRPM7

Synonym

CHAK1, Transient receptor potential cation channel subfamily M member 7, LTRPC7

Scientific Information

Q96QT4 (http://www.uniprot.org/uniprot/Q96QT4)

Assay Properties

Substrates

MBP (Myelin Basic Protein), 20 µM
ATP, 10 µM

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Screening Location

Malvern, PA, USA

Further Information

More information can be found on our website Kinase Assays

Reference compound IC50 for TRPM7/CHAK1