NNMT for direct binding screening and profiling of test substance with surface plasmon resonance (SPR) technique.
Target Overview
Target
NNMT
HGNC Symbol
NNMT
Synonyms
Nicotinamide N-methyltransferase
Scientific Information
P40261 (https://www.uniprot.org/uniprotkb/P40261)
Protein Source
Produced at Reaction Biology. Catalog #MT-11-358
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website SPR Assay Services for Drug Discovery.
SAM binding to NNMT
The data were collected on a Biacore 8K using multi-cycle kinetics. The data were analyzed using a steady state affinity model.
The data were collected on a Biacore 8K using multi-cycle kinetics. The data were analyzed using a steady state affinity model.
JBSNF binding to NNMT
The data were collected on a Biacore 8K using single-cycle kinetics. The data were analyzed using a 1:1 kinetic binding model.