ABL1 (G250E) Kinase Assay Service

Activity-based ABL1 (G250E) kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
ABL1 (G250E)
Enzyme
Human ABL1 (G250E)
HGNC
ABL1 (G250E)
Synonym
ABL, JTK7, p150, c-ABL, v-abl
Substrates
Peptide substrate, [EAIYAAPFAKKK], 20 µM
ATP, 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
Scientific Information
P00519 (http://www.uniprot.org/uniprot/P00519)
Screening Location
Malvern, USA
Reference compound IC50 for ABL1 (G250E)