ABL2/ARG Kinase Assay Service

Activity-based ABL2/ARG kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

ABL2

Enzyme

Human ABL2

HGNC

ABL2

Synonym

ABLL, ARG

Substrates

Peptide substrate, [EAIYAAPFAKKK], 20 µM
ATP, 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

P42684 (http://www.uniprot.org/uniprot/P42684)

Screening Location

Malvern, USA

Reference compound IC50 for ABL2/ARG