ACC1

Carboxylase assay
CAT#
ACC1
Synonyms
Acetyl-CoA carboxylase 1, ACACA, ACC-alpha, Biotin carboxylase
Enzyme
Human ACC1
Substrate
Acetyl-CoA, 10 μMATP 10 μM
Reaction
Acetyl-CoA + ATP + HCO₃⁻ = Malonyl-CoA + ADP + Pi
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
CP 6401861,950
ACC2 Inhibitor12,600
Scientific Information
Q13085 (http://www.uniprot.org/uniprot/Q13085)
Compound IC50 for ACC1
Compound IC50 for ACC1