Adam-10 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Adam-10
Enzyme
Adam-10
Synonym
Disintegrin and metalloproteinase domain-containing protein 10, CDw156, Kuzbanian protein homolog, Mammalian disintegrin-metalloprotease, KUZ, MADM
Molecular Weight
52 kDa
Substrates
Fluorogenic substrate MCA-PLAQAV-Dpa-RSSSR-NH2, 10 µM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (µM) |
|---|---|
| GM6001 | 0.526 |
Scientific Information
O14672 (https://www.uniprot.org/uniprotkb/O14672/entry)
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assay Services
Reference compound IC50 for Adam-10
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