ALK2/ACVR1 Kinase Assay Service

Activity-based ALK2/ACVR1 kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

ALK2/ACVR1

Enzyme

Human ALK2/ACVR1

HGNC

ACVR1

Synonym

ACTRI, ACVRLK2, ALK2, SKR1

Substrates

Casein, 1 mg/ml
ATP 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

Q04771 (http://www.uniprot.org/uniprot/Q04771)

Screening Location

Malvern, USA

Reference compound IC50 for ALK2/ACVR1