ALK4/ACV1B Kinase Assay Service

Activity-based ALK4/ACV1B kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

ALK4

Enzyme

Human ALK4

HGNC

ACVR1B

Synonym

ACTRIB, ACVRLK4, ALK4, SKR2

Substrates

Casein, 1 mg/ml
ATP 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

P36896 (http://www.uniprot.org/uniprot/P36896)

Screening Location

Malvern, USA

Reference compound IC50 for ALK4/ACVR1B