ALK1/ACVRL1 Kinase Assay Service

Activity-based ALK1/ACVRL1 kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

ALK1

Enzyme

Human ALK1

HGNC

ACVRL1

Synonym

ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3

Substrates

Casein, 20 mg/ml
ATP 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

P37023 (http://www.uniprot.org/uniprot/P37023)

Screening Location

Malvern, USA

Reference compound IC50 for ALK1/ACVRL1