Activity-based ATM kinase assay for compound screening and profiling using HTRF kinase assay.
Target Overview
CAT#
ATM
Enzyme
Human ATM
HGNC
ATM
Synonym
TEL1, TELO1
Substrates
p53, 100 nMATP 10 µM
Assay Properties
Reaction
Substrate + ATP = P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
Scientific Information
Q13315 (http://www.uniprot.org/uniprot/Q13315)
Screening Location
Malvern, USA
Reference compound IC50 for ATM
