AVPR1A Functional Cell Reporter Agonist Assay for compound screening and profiling via luminescence recordings.
Target Overview
CAT#
AVPR1A Functional Agonist
GPCR Target
Human AVPR1A
Cell Line
Proprietary human cells engineered to constitutively express AVPR1A
Scientific Information
V1AR (https://www.uniprot.org/uniprotkb/P37288/entry)
Assay Properties
Protocol
Cells expressing AVPR1A incubated with agonist for 24 h; luminescence measurement 30 min post application of detection reagent
Readout
Luminescence tracking changes in NFAT activity on Envision plate reader
Reference Compound EC50
| Compound EC50 (nM) |
|---|
| Vasopressin (0.0201) |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website In Vitro Safety Pharmacology Profiling
Reference compound activation of AVPR1A
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