AXL (R499C) Kinase Assay Service

Activity-based AXL (R499C) kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

AXL (R499C)

Enzyme

Human AXL (R499C)

HGNC

AXL (R199C)

Synonym

EC, UFO

Substrates

Peptide substrate, [EAIYAAPFAKKK], 20 µM
ATP, 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

P30530 (http://www.uniprot.org/uniprot/P30530)

Screening Location

Malvern, USA

Reference compound IC50 for AXL (R499C)