Surface Plasmon Resonance (SPR) technique for evaluating direct binding of small molecule inhibitors to BCL-W
Target Overview
Target
Bcl-2-like protein 2
HGNC symbol
BCL2L2
Synonyms
BCLW, KIAA0271
Scientific information
Q92843 (https://www.uniprot.org/uniprot/Q92843)
Protein source
Produced at Reaction Biology
Screening location
Malvern, PA, USA
Further information
More information can be found on our website SPR Assay Services for Drug Discovery
Binding kinetics of ABT-737 to BCL-W
The data was collected on a Biacore 8K using single-cycle kinetics. The data was analyzed using a 1:1 kinetic binding model.
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