BCL-xL Apoptosis Assay for compound screening and profiling using HTRF to measure compound binding to the target.
Target Overview
CAT#
BCL-xL
Enzyme
Human BCL-xL
Synonyms
Bcl-2-like protein 1, Bcl2-L-1, Apoptosis regulator Bcl-X, BCL2L1, BCL2L, BCLX
Substrates
Bad peptide, 40 nM
Assay Properties
Reaction
Competition binding assay with Bad peptide in HTRF assay.
Reference Compound IC50s
Scientific Information
Q07817 (http://www.uniprot.org/uniprot/Q07817)
Screening Location
Malvern, USA
Bad peptide displacement IC50 for BCL-xL
