Activity-based BMPR1A kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology
Target Overview
RBE Target ID
BMPR1A
Enzyme
Human BMPR1A, wt
HGNC
BMPR1A
Manning ID
BMPR1A
Synonym
ACVRLK3, ALK3, BMPR1A, SKR5, CD292, ALK3, ALK3/BMPR1A
UniProt
P36894 (BMR1A_HUMAN)
Kinase Type
Protein kinase
Kinase Group
TKL
Assay Properties
Assay Format
33PanQinaseTM
Substrates
Casein, ATP
Reaction
Casein + 33P-ATP = 33P-Casein + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Staurosporine | 63000 |
| Sorafenib | 10000 |
| Sunitinb | 100000 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | BMPR1A |
| 345 wt Profiler | Yes |
| 345 IC50 wt Profiler | Yes |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | No |
| IC50 Profiler | No |
Recombinant Protein Availability
| Active recombinant protein | Yes; ProQinaseTM – BMPR1A (Activity verified by 33PanQinaseTM-Assay) |
| Product Number | 1655-0000-1 |
| Web Shop | Reaction Biology Online Shop |
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