BRD1-His Reader Domain Assay for compound screening and profiling using the AlphaScreen assay format to measure compound binding to the target.
Target Overview
CAT#
BRD1
Enzyme
Human BRD1
Synonyms
Bromodomain-containing protein 1, BR140-like protein, Bromodomain and PHD finger-containing protein 2, BRL, BRPF2
Substrates
Histone H4 peptide (1-21) K5/8/12/16Ac
Assay Properties
Reaction
AlphaScreen Binding assay
Readout
Fluorescence
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| PFI-1 | 20,000 |
| Bromosporine | 1,700 |
Scientific Information
O95696 (http://www.uniprot.org/uniprot/O95696)
Screening Location
Malvern, USA
Further information
More information can be found on our website Reader Domain Assay Services.
Reference Compound IC50 for BRD1
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