BRD2-1 Bromodomain Assay Service (AlphaScreen)

BRD2-1-His Reader Domain Assay for compound screening and profiling using the AlphaScreen assay format to measure compound binding to the target.

Target Overview

CAT#

BRD2-1

Enzyme

Human BRD2-1

Synonyms

Bromodomain-containing protein 2 domain 1, O27.1.1, Really interesting new gene 3 protein, KIAA9001, RING3

Substrates

Histone H4 peptide (1-21) K5/8/12/16Ac

Assay Properties

Reaction

AlphaScreen Binding assay

Readout

Fluorescence

Reference Compound IC50s
Compounds IC50 (nM)
JQ-1 55
PFI-1 175

Scientific Information

P25440 (http://www.uniprot.org/uniprot/P25440)

Screening Location

Malvern, USA

Further information

More information can be found on our website Reader Domain Assay Services.

Reference Compound IC50 for BRD2-1

Reference Compound IC50 for BRD2-1