BRDT-Tndm-His Reader Domain Assay for compound screening and profiling using the AlphaScreen assay format to measure compound binding to the target.
Target Overview
CAT#
BRDT-Tandem
Enzyme
Human BRDT-Tandem
Synonyms
Bromodomain testis-specific protein domain 1 and domain 2, Cancer/testis antigen 9, RING3-like protein
Substrates
Histone H4 peptide (1-21) K5/8/12/16Ac
Assay Properties
Reaction
AlphaScreen Binding assay
Readout
Fluorescence
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| JQ-1 | 120 |
| PFI-1 | 550 |
Scientific Information
Q58F21 (http://www.uniprot.org/uniprot/Q58F21)
Screening Location
Malvern, USA
Further information
More information can be found on our website Reader Domain Assay Services.
Reference Compound IC50 for BRDT-T
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