Calpain 1 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Calpain 1
Enzyme
Calpain 1
Synonym
Calcium-activated neutral proteinase 1, Calpain mu-type, Calpain-1 large subunit, Cell proliferation-inducing gene 30 protein, Micromolar calpain, CAN1, CAPN1, CANPL1
Substrates
Fluorogenic substrate N-Succinyl-LY-AMC, 10 µM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| E-64 | 20.2 |
Scientific Information
P07384 (https://www.uniprot.org/uniprotkb/P07384/entry)
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assay Services.
Reference compound IC50 for Calpain 1
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