Activity-based CAMKK1 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology
Target Overview
RBE Target ID
CAMKK1
Enzyme
Human CAMKK1, wt
HGNC
CAMKK1
Manning ID
CaMKK1
Synonym
CAMKKA, DKFZp761M0423, MGC34095, CAMKK1
UniProt
Q8N5S9 (KKCC1_HUMAN)
Kinase Type
Protein kinase
Kinase Group
Other
Assay Properties
Assay Format
33PanQinaseTM
Substrates
RB-CTF, ATP
Reaction
RB-CTF + 33P-ATP = 33P-RB-CTF + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Staurosporine | 23 |
| Sorafenib | 10000 |
| Sunitinib | 2700 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | CAMKK1 |
| 355 wt Profiler | Yes |
| 355 IC50 wt Profiler | Yes |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | No |
| IC50 Profiler | No |
Recombinant Protein Availability
| Active recombinant protein | No |
| Product Number | N/A |
| Web Shop | Reaction Biology Online Shop |
PDF