Caspase 1 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Caspase 1
Enzyme
Human Caspase 1
Synonym
Interleukin-1 beta convertase, p45, CASP1, IL1BC, IL1BCE
Substrates
Fluorogenic peptide Ac-LEHD-AMC, 5 µM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| IETD-CHO | 17.1 |
Scientific Information
P29466 (https://www.uniprot.org/uniprotkb/P29466/entry)
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assay Services.
Reference compound IC50 for Caspase 1
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