PROTAC mediated ternary complex formation between Cereblon/DDB1 complex and target protein.
Target Overview
CAT#
Cereblon-ternary
Enzyme
Cereblon/DDB1
Scientific Information
Assay Properties
Reaction
Cereblon/DDB1 + PROTAC + Target = Ternary Complex
Readout
HTRF
Reference Compound IC50s
dBET1, dBET6 for selected bromodomain; otherwise target specific
Screening Location
Malvern, PA, USA
Further information
More information can be found on our website Protein Degradation Assay – PROTAC Screening
Reference compound example for Cereblon
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