cIAP-1 Apoptosis Assay for compound screening and profiling using fluorescence polarization to measure compound binding to the target.
Target Overview
CAT#
cIAP-1
Enzyme
Human cIAP-1 BIR3 domain
Synonyms
Baculoviral IAP repeat-containing protein 2, Cellular inhibitor of apoptosis 1, RING-type E3 ubiquitin transferase BIRC2, IAP homolog B, BIRC2
Substrates
Fluorescence-labeled Probe, 5 nM
Assay Properties
Reaction
Competition binding assay with probe in FP assay.
Reference Compound IC50s
Scientific Information
Q13490 (http://www.uniprot.org/uniprot/Q13490)
Screening Location
Malvern, USA
Probe displacement IC50 for cIAP-1
