Activity-based CK1epsilon kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology
Target Overview
RBE Target ID
CK1epsilon
Enzyme
Human CK1epsilon, wt
HGNC
CSNK1E
Manning ID
CK1e
Synonym
CK1-epsilon, CKIe, HCKIE, MGC10398, CSNK1E, CK1epsilon
UniProt
P49674 (KC1E_HUMAN)
Kinase Type
Protein kinase
Kinase Group
CK1
Assay Properties
Assay Format
33PanQinaseTM
Substrates
Casein, ATP
Reaction
Casein + 33P-ATP = 33P-Casein + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Sorafenib | 10000 |
| Sunitinib | 950 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | CK1epsilon |
| 355 wt Profiler | Yes |
| 355 IC50 wt Profiler | Yes |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | No |
| IC50 Profiler | No |
Recombinant Protein Availability
| Active recombinant protein | No |
| Product Number | N/A |
| Web Shop | Reaction Biology Online Shop |
PDF