CK1g2 Kinase Assay Service - Reaction Biology

Activity-based CK1g2 kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

CK1g2

Enzyme

Human CK1g2

HGNC

CSNK1G2

Synonym

CK1g2, CK1-gamma2

Substrates

Peptide substrate, [KRRRAL[pS]VASLPGL], 20 µM
ATP 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

P78368 (http://www.uniprot.org/uniprot/P78368)

Screening Location

Malvern, USA

Reference compound IC50 for CK1γ2