Activity-based CK1gamma3 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology
Target Overview
RBE Target ID
CK1gamma3
Enzyme
Human CK1gamma3, wt
HGNC
CSNK1G3
Manning ID
CK1g3
Synonym
CK1-gamma3, CSNK1G3, CK1gamma3, CK1g3
UniProt
Q9Y6M4 (KC1G3_HUMAN)
Kinase Type
Protein kinase
Kinase Group
CK1
Assay Properties
Assay Format
33PanQinaseTM
Substrates
Casein, ATP
Reaction
Casein + 33P-ATP = 33P-Casein + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Staurosporine | 9833 |
| Sorafenib | 10000 |
| Sunitinb | 1500 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | CK1gamma3 |
| 345 wt Profiler | Yes |
| 345 IC50 wt Profiler | Yes |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | No |
| IC50 Profiler | No |
Recombinant Protein Availability
| Active recombinant protein |
No |
| Product Number | N/A |
| Web Shop | Reaction Biology Online Shop |
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