Activity-based CK2alpha2 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology
Target Overview
RBE Target ID
CK2alpha2
Enzyme
Human CK2alpha2, wt
HGNC
CSNK2A2
Manning ID
CK2a2
Synonym
CK2-alpha2, CSNK2A2, CK2alpha2, CK2a2
UniProt
P19784 (CSK22_HUMAN)
Kinase Type
Protein kinase
Kinase Group
Other
Assay Properties
Assay Format
33PanQinaseTM
Substrates
Casein, ATP
Reaction
Casein + 33P-ATP = 33P-Casein + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Staurosporine | 3600 |
| Sorafenib | 10000 |
| Sunitinib | 23000 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | CK2alpha2 |
| 355 wt Profiler | Yes |
| 355 IC50 wt Profiler | Yes |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | No |
| IC50 Profiler | No |
Recombinant Protein Availability
| Active recombinant protein | Yes; ProQinaseTM – CK2alpha2 (Activity verified by 33PanQinaseTM-Assay) |
| Product Number | 0412-0000-1 |
| Web Shop | Reaction Biology Online Shop |
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