CLK2 Kinase Activity Assay Service

Activity-based CLK2 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview
RBE Target ID

CLK2

Enzyme

Human CLK2, wt

HGNC

CLK2

Manning ID

CLK2

Synonym

MGC61500, clk2, hCLK2, CLK2

UniProt

P49760 (CLK2_HUMAN)

Kinase Type

Protein kinase

Kinase Group

CMGC

Assay Properties
Assay Format

33PanQinaseTM

Substrates

RBER-GSK3(14-27), ATP

Reaction

RBER-GSK3(14-27) + 33P-ATP = 33P-RBER-GSK3(14-27) + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 51
Sorafenib 10000
Sunitinib 190
Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability
Screening Opportunities
FreeChoice CLK2
355 wt Profiler Yes
355 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein No
Product Number N/A
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