CREBBP-His Reader Domain Assay for compound screening and profiling using the AlphaScreen assay format to measure compound binding to the target.
Target Overview
CAT#
CREBBP-His
Enzyme
Human CREBBP-His
Synonyms
CREB-binding protein, CBP)
Substrates
Histone H4 peptide (1-21) K5/8/12/16Ac
Assay Properties
Reaction
AlphaScreen Binding assay
Readout
Fluorescence
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| JQ-1 | 15,000 |
| PFI-1 | 6,700 |
| Bromosporine | 2,200 |
| SGC-CBP30 | 75 |
Scientific Information
Q92793 (http://www.uniprot.org/uniprot/Q92793)
Screening Location
Malvern, USA
Further information
More information can be found on our website Reader Domain Assay Services.
Reference Compound IC50 for CREBBP
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