CREBBP Bromodomain SPR Assay Service

Binding assay for CREB-binding protein using a surface plasmon resonance (SPR) technique

Target Overview

Target

CREB-binding protein (Bromodomain), AA 1081-1197

HGNC symbol

CREBBP

Synonyms

Histone lysine acetyltransferase CREBBP, Protein-lysine acetyltransferase CREBBP

Uniprot page

Q92793 (https://www.uniprot.org/uniprot/Q92793)

Screening location

Malvern, PA, USA

Further information

More information can be found on our website SPR Assay Services for Drug Discovery

Binding kinetics of reference compound (I-CPB 112) to the Bromodomain of CREB-binding protein

CREBBP SPR

The data was collected on a Biacore 8K using multi-cycle kinetics. Reduced DMSO conditions were used. The data was analyzed using a steady state affinity model.