Activity-based CSK kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology
Target Overview
RBE Target ID
CSK
Enzyme
Human CSK, wt
HGNC
CSK
Manning ID
CSK
Synonym
CSK
UniProt
P41240 (CSK_HUMAN)
Kinase Type
Protein kinase
Kinase Group
TK
Assay Properties
Assay Format
33PanQinaseTM
Substrates
PolyEY, ATP
Reaction
PolyEY + 33P-ATP = 33P-PolyEY + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
Compounds | IC50 (nM) |
---|---|
Staurosporine | 207 |
Sorafenib | 8300 |
Sunitinib | 19000 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
FreeChoice | CSK |
355 wt Profiler | Yes |
355 IC50 wt Profiler | Yes |
Mutant Profiler Addon | No |
Lipid Kinase Profiler Addon | No |
IC50 Profiler | No |
Recombinant Protein Availability
Active recombinant protein | Yes; ProQinaseTM – CSK (Activity verified by 33PanQinaseTM-Assay) |
Product Number | 0266-0000-1 |
Web Shop | Reaction Biology Online Shop |
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