CSK Kinase Assay Service

Activity-based CSK kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
CSK

Enzyme
Human CSK

HGNC
CSK

Synonym
CSK

Substrates
Peptide substrate, poly[Glu:Tyr] (4:1), 0.2 mg/ml
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Staurosporine 14.6
PP2 142
AG1478 3,200
D-64406 9,500
Scientific Information
P41240 (http://www.uniprot.org/uniprot/P41240)

Screening Location
Malvern, USA

Reference compound IC50 for CSK
Reference compound IC50 for CSK

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