CYP2C9 for compound screening and profiling via fluorescence-based cytochrome P450 inhibition assay quantification of enzyme activity.
Target Overview
CAT#
CYP2C9
Enzyme
Cyp2C9 + NADPH-P450 Reductase (microsomes from insect cells infected with baculovirus containing the human CYP2C9 cDNA and rabbit Cytochrome P450 cDNA)
Synonym
Cytochrome P450, family 2, subfamily C, polypeptide 9
Substrate
Fluorescence Substrate Vivid® OOMR
Assay Properties
Reaction
RH + O₂ + NADPH + H⁺ = ROH + H₂O + NADP⁺
Readout
Enzymatic activity
Reference Compound IC50s
Scientific Information
P11712 (https://www.uniprot.org/uniprotkb/P11712/entry)
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website CYP450 Inhibition Assay Services.
Reference compound IC50 for CYP2C9
