EIF2AK4 Kinase Activity Assay Service

Activity-based EIF2AK4 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview
RBE Target ID

EIF2AK4

Enzyme

Human EIF2AK4, wt

HGNC

EIF2AK4

Manning ID

GCN2

Synonym

GCN2, KIAA1338

UniProt

Q9P2K8 (E2AK4_HUMAN)

Kinase Type

Protein kinase

Kinase Group

Other

Assay Properties
Assay Format

33PanQinaseTM

Substrates

RB-S6P, ATP

Reaction

RB-S6P + 33P-ATP = 33P-RB-S6P + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 160
Sorafenib 10000
Sunitinib 7800
Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability
Screening Opportunities
FreeChoice EIF2AK4
355 wt Profiler No
355 IC50 wt Profiler No
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein Yes; ProQinaseTM – EIF2AK4
(Activity verified by 33PanQinaseTM-Assay)
Product Number 1504-0000-1
Web Shop Reaction Biology Online Shop